[Inhibitory effect of chloroquine on airway hyperresponsiveness in asthmatic mice].
Identifieur interne : 000E67 ( Main/Exploration ); précédent : 000E66; suivant : 000E68[Inhibitory effect of chloroquine on airway hyperresponsiveness in asthmatic mice].
Auteurs : Xiao-Chun Sun [Oman] ; Xiao-Yan Hu ; Li-Jia Wang ; En-Mei Liu ; Zhou FuSource :
- Nan fang yi ke da xue xue bao = Journal of Southern Medical University [ 1673-4254 ] ; 2015.
Descripteurs français
- KwdFr :
- Animaux, Asthme (), Asthme (traitement médicamenteux), Chloroquine (pharmacologie), Dexaméthasone (pharmacologie), Dinoprost (métabolisme), Granulocytes neutrophiles (cytologie), Granulocytes éosinophiles (cytologie), Inflammation (anatomopathologie), Interleukine-6 (métabolisme), Liquide de lavage bronchoalvéolaire (cytologie), Modèles animaux de maladie humaine, Numération des leucocytes, Poumon (anatomopathologie), Souris, Souris de lignée BALB C, Test ELISA.
- MESH :
- anatomopathologie : Inflammation, Poumon.
- cytologie : Granulocytes neutrophiles, Granulocytes éosinophiles, Liquide de lavage bronchoalvéolaire.
- métabolisme : Dinoprost, Interleukine-6.
- pharmacologie : Chloroquine, Dexaméthasone.
- traitement médicamenteux : Asthme.
- Animaux, Asthme, Modèles animaux de maladie humaine, Numération des leucocytes, Souris, Souris de lignée BALB C, Test ELISA.
English descriptors
- KwdEn :
- Animals, Asthma (chemically induced), Asthma (drug therapy), Bronchoalveolar Lavage Fluid (cytology), Chloroquine (pharmacology), Dexamethasone (pharmacology), Dinoprost (metabolism), Disease Models, Animal, Enzyme-Linked Immunosorbent Assay, Eosinophils (cytology), Inflammation (pathology), Interleukin-6 (metabolism), Leukocyte Count, Lung (pathology), Mice, Mice, Inbred BALB C, Neutrophils (cytology).
- MESH :
- chemical , metabolism : Dinoprost, Interleukin-6.
- chemical , pharmacology : Chloroquine, Dexamethasone.
- chemically induced : Asthma.
- cytology : Bronchoalveolar Lavage Fluid, Eosinophils, Neutrophils.
- drug therapy : Asthma.
- pathology : Inflammation, Lung.
- Animals, Disease Models, Animal, Enzyme-Linked Immunosorbent Assay, Leukocyte Count, Mice, Mice, Inbred BALB C.
Abstract
To investigate the effect of chloroquine on airway hyperresponsiveness in asthmatic mice and explore the possible mechanism.
PubMed: 25613602
Affiliations:
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- to stream Ncbi, to step Curation: 000274
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Le document en format XML
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<author><name sortKey="Sun, Xiao Chun" sort="Sun, Xiao Chun" uniqKey="Sun X" first="Xiao-Chun" last="Sun">Xiao-Chun Sun</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Respiratory Medicine, Children's Hospital Affiliated to Chongqing Medical University, Chongqing 400014, China.E-mail: 1103751123@qq.com.</nlm:affiliation>
<country wicri:rule="url">Oman</country>
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<author><name sortKey="Hu, Xiao Yan" sort="Hu, Xiao Yan" uniqKey="Hu X" first="Xiao-Yan" last="Hu">Xiao-Yan Hu</name>
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<author><name sortKey="Wang, Li Jia" sort="Wang, Li Jia" uniqKey="Wang L" first="Li-Jia" last="Wang">Li-Jia Wang</name>
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<author><name sortKey="Liu, En Mei" sort="Liu, En Mei" uniqKey="Liu E" first="En-Mei" last="Liu">En-Mei Liu</name>
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<author><name sortKey="Fu, Zhou" sort="Fu, Zhou" uniqKey="Fu Z" first="Zhou" last="Fu">Zhou Fu</name>
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<author><name sortKey="Liu, En Mei" sort="Liu, En Mei" uniqKey="Liu E" first="En-Mei" last="Liu">En-Mei Liu</name>
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<term>Asthma (drug therapy)</term>
<term>Bronchoalveolar Lavage Fluid (cytology)</term>
<term>Chloroquine (pharmacology)</term>
<term>Dexamethasone (pharmacology)</term>
<term>Dinoprost (metabolism)</term>
<term>Disease Models, Animal</term>
<term>Enzyme-Linked Immunosorbent Assay</term>
<term>Eosinophils (cytology)</term>
<term>Inflammation (pathology)</term>
<term>Interleukin-6 (metabolism)</term>
<term>Leukocyte Count</term>
<term>Lung (pathology)</term>
<term>Mice</term>
<term>Mice, Inbred BALB C</term>
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<term>Chloroquine (pharmacologie)</term>
<term>Dexaméthasone (pharmacologie)</term>
<term>Dinoprost (métabolisme)</term>
<term>Granulocytes neutrophiles (cytologie)</term>
<term>Granulocytes éosinophiles (cytologie)</term>
<term>Inflammation (anatomopathologie)</term>
<term>Interleukine-6 (métabolisme)</term>
<term>Liquide de lavage bronchoalvéolaire (cytologie)</term>
<term>Modèles animaux de maladie humaine</term>
<term>Numération des leucocytes</term>
<term>Poumon (anatomopathologie)</term>
<term>Souris</term>
<term>Souris de lignée BALB C</term>
<term>Test ELISA</term>
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<term>Interleukin-6</term>
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<term>Dexamethasone</term>
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<term>Poumon</term>
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<keywords scheme="MESH" qualifier="chemically induced" xml:lang="en"><term>Asthma</term>
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<keywords scheme="MESH" qualifier="cytologie" xml:lang="fr"><term>Granulocytes neutrophiles</term>
<term>Granulocytes éosinophiles</term>
<term>Liquide de lavage bronchoalvéolaire</term>
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<keywords scheme="MESH" qualifier="cytology" xml:lang="en"><term>Bronchoalveolar Lavage Fluid</term>
<term>Eosinophils</term>
<term>Neutrophils</term>
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<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Asthma</term>
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<keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Dinoprost</term>
<term>Interleukine-6</term>
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<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Inflammation</term>
<term>Lung</term>
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<keywords scheme="MESH" qualifier="pharmacologie" xml:lang="fr"><term>Chloroquine</term>
<term>Dexaméthasone</term>
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<term>Disease Models, Animal</term>
<term>Enzyme-Linked Immunosorbent Assay</term>
<term>Leukocyte Count</term>
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<term>Mice, Inbred BALB C</term>
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<term>Asthme</term>
<term>Modèles animaux de maladie humaine</term>
<term>Numération des leucocytes</term>
<term>Souris</term>
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<front><div type="abstract" xml:lang="en">To investigate the effect of chloroquine on airway hyperresponsiveness in asthmatic mice and explore the possible mechanism.</div>
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<name sortKey="Hu, Xiao Yan" sort="Hu, Xiao Yan" uniqKey="Hu X" first="Xiao-Yan" last="Hu">Xiao-Yan Hu</name>
<name sortKey="Liu, En Mei" sort="Liu, En Mei" uniqKey="Liu E" first="En-Mei" last="Liu">En-Mei Liu</name>
<name sortKey="Wang, Li Jia" sort="Wang, Li Jia" uniqKey="Wang L" first="Li-Jia" last="Wang">Li-Jia Wang</name>
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<country name="Oman"><noRegion><name sortKey="Sun, Xiao Chun" sort="Sun, Xiao Chun" uniqKey="Sun X" first="Xiao-Chun" last="Sun">Xiao-Chun Sun</name>
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